National Institutes of Health · General
NIH Research Project Grant (R01)
NIH's flagship investigator-initiated research grant. Funds discrete, specified, circumscribed health-related research projects in the principal investigator's areas of interest. Submitted by the institution on behalf of the PI; the most common funding mechanism across NIH institutes.
Program facts
- Typical award
- $250K – $500K
- Non-federal match
- Varies by NOFO
- Audience
- Local governments and eligible subrecipients
- Application window
- Standard NIH receipt dates February / June / October; specific RFAs/PARs vary.
- Typical prep time
- 10–18 weeks
- Statutory authority
- Public Health Service Act §301 (42 U.S.C. §241) and §487 (42 U.S.C. §288)
Catalog entry last verified 2026-05-27 · Verify on the agency page →
Eligibility at a glance
- Institutions of higher education are eligible applicants.
Modular budgets capped at $250K direct/yr; non-modular budgets higher and require detailed justification. Amounts and timing approximate; verify directly with administering agency.
How Strategic Pursuit scores this program
When you run a city dossier, Strategic Pursuit cross-checks the city's demographics, federal award history, disaster history, and CEJST burden categories against this program's eligibility and strategic-fit signals. You see an explicit eligibility / strategic / competitive grade — backed by source citations — instead of a generic "match" badge.
Planning purposes only. Award ranges, match percentages, and application windows on this page summarize the latest publicly available agency guidance and are approximate. Always verify the binding NOFO on the administering agency's page before applying.